The Role of Estrogen and Dehydroepiandrosterone in Synaptic Remodeling
نویسنده
چکیده
Kiel J, Leranth C (2006) Synaptic remodeling induced by gonadal hormones: neuronal plasticity as a mediator of neuroendocrine and behavioral responses to (2007) Fluctuation of synapse density in the arcuate nucleus during the estrus cycle. Estradiol-induced synaptic remodeling of tyrosine hydroxylase immunopositive neurons in the rat arcuate nucleus. Endocrinology. 2008 Apr 17. Epub ahead of print.
منابع مشابه
Estrogen and Progesterone Replacement Therapy Prevent Methamphetamine-Induced Synaptic Plasticity Impairment in Ovariectomized Rats
Background: Methamphetamine (METH) is one of the most popular psychostimulants which produce long lasting learning and memory impairment. Previous studies have indicated that estrogen and progesterone replacement therapy attenuate cognitive impairment against a wide array of neurodegenerative diseases. Present study was designed to figure out the effects of estrogen, progesterone alone or in co...
متن کاملRole of Nuclear Receptors Steroidogenic Factor-1, DAX-1, and Estrogen Receptor
Steroid hormone biosynthesis by the fetal adrenal gland is crucial to the integrity and continuation of pregnancy, growth of the fetal and maternal tissues, as well as perinatal homeostatic adaptation for extrauterine survival. The adrenal cortex in the primate undergoes a remarkable morphological and functional remodeling such that the fetal adrenal cortex transforms into an adult adrenal cort...
متن کاملAdrenal Organogenesis and 2 Steroidogenesis Role of Nuclear Receptors Steroidogenic Factor-1, DAX-1, and Estrogen Receptor
Steroid hormone biosynthesis by the fetal adrenal gland is crucial to the integrity and continuation of pregnancy, growth of the fetal and maternal tissues, as well as perinatal homeostatic adaptation for extrauterine survival. The adrenal cortex in the primate undergoes a remarkable morphological and functional remodeling such that the fetal adrenal cortex transforms into an adult adrenal cort...
متن کاملSex differences in the pulmonary circulation: implications for pulmonary hypertension.
Pulmonary arterial hypertension (PAH), a form of pulmonary hypertension, is a complex disease of multifactorial origin. While new developments regarding pathophysiological features and therapeutic options in PAH are being reported, one important fact has emerged over the years: there is a sex difference in the incidence of this disease such that while there is a higher incidence in females, dis...
متن کاملLocal production of sex hormones and their modulation of hippocampal synaptic plasticity.
It is believed that sex hormones are synthesized in the gonads and reach the brain via the blood circulation. In contrast with this view, the authors have demonstrated that sex hormones are also synthesized locally in the hippocampus and that these steroids act rapidly to modulate neuronal synaptic plasticity. The authors demonstrated that estrogens are locally synthesized from cholesterol thro...
متن کامل